Welcome to the Liu Laboratory

In the Liu Lab, our goal is to decode the genetic and epigenetic basis of human aging and age-related diseases. Our research is founded on the principle that obtaining a comprehensive understanding of genome regulatory circuits at the system level is crucial for deciphering the underlying causal genetic and molecular factors in human disease.

Our research leverages state-of-the-art sequencing technologies alongside innovative machine-learning models to decode genetic and epigenetic regulatory networks. Our distinctive approach lies in harmonizing data from genome-wide association studies with insights from the functional genome and single-cell epigenome analysis. This comprehensive integration is pivotal in pinpointing regulatory genome elements, disease-causal genes, cell types, and potential targets for drug development.

We welcome the opportunity to forge extensive collaborations with biologists both locally and internationally, aiming to contribute groundbreaking biological insights that foster healthy aging. If you share our dedication to advancing wellness across all ages through rigorous research, we invite you to partner with us in this endeavor.

Research for Healthy Aging

Wellness at every age

Department of Biomedical Genetics & University of Rochester Aging Institute